Global Health: Science and Practice (GHSP) is a no-fee, open access, peer-reviewed online journal intended to be a resource for public health professionals who design, implement, manage, evaluate, and otherwise support health programs in low- and middle-income countries. Published quarterly since 2013, GHSP fills an important gap in the scholarly literature for evidence and experience from global health programs implemented under real-world conditions, with specifics on the “how” of implementation—lessons and detail that are often buried in gray literature or not documented at all. One of GHSP’s primary objectives is to increase the inclusion of voices and perspectives from low- and middle- income countries in global health work and the published material arising from such work. GHSP includes articles on all global health topics and a wide range of cross-cutting issues. GHSP recently received its first Impact Factor of 2.352 in the 2019 Journal Citation Report from the Web of Science Group and is indexed in PubMed, PubMed Central, Web of Science Social Sciences Citation Index, and many others. GHSP is published by the Johns Hopkins Center for Communication Programs and the University of Alberta, School of Public Health with funding from USAID under the Knowledge SUCCESS (Strengthening Use, Capacity, Collaboration, Exchange, Synthesis, and Sharing) Project.